About Triple-negative breast cancer (TNBC)

What are the treatments for Triple-negative breast cancer (TNBC)?

The treatment options for triple-negative breast cancer (TNBC) typically include a combination of surgery, radiation therapy, chemotherapy, and targeted therapy. However, it's important to note that treatment plans may vary depending on the stage and characteristics of the cancer, as well as individual patient factors. Here are some common treatment approaches for TNBC:

1. Surgery: The primary treatment for TNBC is usually surgery, which involves removing the tumor and nearby lymph nodes. The type of surgery may vary, ranging from lumpectomy (removal of the tumor) to mastectomy (removal of the entire breast).

2. Radiation therapy: After surgery, radiation therapy may be recommended to destroy any remaining cancer cells and reduce the risk of recurrence. It involves using high-energy X-rays or other radiation sources to target the affected area.

3. Chemotherapy: TNBC is often treated with chemotherapy

What are the risk factors for Triple-negative breast cancer (TNBC)?

There are several risk factors associated with triple-negative breast cancer (TNBC). These include:

1. Gender: TNBC is more common in women than in men. Although men can also develop TNBC, it is predominantly found in women.

2. Age: TNBC is more likely to occur in younger women, typically under the age of 50. However, it can affect women of any age.

3. Family history: Having a family history of breast cancer, particularly in first-degree relatives (such as a mother, sister, or daughter), increases the risk of developing TNBC. This risk is further elevated if the family member was diagnosed at a young age or had bilateral breast cancer.

4. Genetic mutations: Certain genetic mutations, such as BRCA1 and BRCA2, are associated with an increased risk of TNBC. These mutations are more commonly found in women

What are the symptoms of Triple-negative breast cancer (TNBC)?

Triple-negative breast cancer (TNBC) is a subtype of breast cancer that lacks the expression of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2). The symptoms of TNBC are similar to other types of breast cancer and may include:

1. Breast lump or mass: A hard, painless lump or Thickening in the breast or underarm area is a common symptom of TNBC. However, not all breast lumps are cancerous.

2. Breast changes: Changes in the size, shape, or appearance of the breast, such as swelling, redness, or dimpling of the skin, may be observed.

3. Nipple changes: Changes in the nipple, such as inversion, flattening, or discharge (other than breast milk), can be a symptom of TNBC.

4.

Is there a cure/medications for Triple-negative breast cancer (TNBC)?

Currently, there is no specific cure for triple-negative breast cancer (TNBC). TNBC is a subtype of breast cancer that lacks estrogen receptors, progesterone receptors, and does not overexpress the HER2 protein. This makes it more challenging to treat compared to other types of breast cancer.

However, there are various treatment options available for TNBC, including chemotherapy, radiation therapy, and surgery. Chemotherapy is the mainstay of treatment for TNBC, and different combinations of drugs may be used depending on the stage and characteristics of the cancer. In some cases, targeted therapies like PARP inhibitors or immunotherapy may also be used.

Research is ongoing to develop more effective treatments for TNBC. Clinical trials are investigating new drugs and treatment approaches specifically targeting TNBC. It is always recommended to consult with a healthcare professional for the most up-to-date information and personalized treatment options.

What is Triple-negative breast cancer (TNBC)?

Triple-negative breast cancer (TNBC) is a subtype of breast cancer that lacks the expression of three specific receptors: estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2). These receptors are typically targeted in other types of breast cancer, but in TNBC, they are not present. This makes TNBC more difficult to treat as it does not respond to hormonal therapies or drugs that target HER2.

TNBC accounts for about 10-20% of all breast cancers and is more commonly diagnosed in younger women, African-American women, and women with BRCA1 gene mutations. It tends to be more aggressive and has a higher risk of recurrence compared to other types of breast cancer.

Due to the lack of specific receptors, treatment options for TNBC are limited. Chemotherapy is the mainstay of treatment,

What are the causes of Triple-negative breast cancer (TNBC)?

The exact causes of triple-negative breast cancer (TNBC) are not fully understood. However, several factors have been identified that may contribute to the development of TNBC:

1. Genetic mutations: In some cases, TNBC may be associated with inherited gene mutations, such as BRCA1 and BRCA2 mutations. These mutations are also linked to an increased risk of ovarian and other cancers.

2. Hormonal factors: TNBC does not have receptors for estrogen, progesterone, or HER2, which are the targets of hormonal and targeted therapies for other types of breast cancer. The absence of these receptors suggests that hormonal factors may not play a significant role in the development of TNBC.

3. Age and gender: TNBC is more commonly diagnosed in younger women, particularly those under the age of 40. It is also more prevalent in African-American women compared to

Video related to Triple-negative breast cancer (TNBC)