Congenital syphilis is a multisystem infection caused by Treponema pallidum and transmitted to the fetus via the placenta. 1. Centers for Disease Control and Prevention (CDC) STI treatment guidelines recommend aqueous crystalline penicillin G 50,000 units/kg IV every 12 hours for the first 7 days of life and every 8 hours thereafter for a total of 10 days or procaine penicillin G 50,000 units/kg IM once/day for 10  Read More