Isotretinoin embryopathy is a pattern of mental and physical birth defects (congenital malformations) that can result from a mother taking retinoids during pregnancy. The absolute risk of congenital malformations following oral isotretinoin therapy is currently unclear. Overall malformation rates in live-born infants from prospectively reported pregnancies range from 5% to 20%.Due to the severity of the birth defec  Read More

Isotretinoin and its commercially available brands, although effective in the treatment of acne, can cause developmental abnormalities in the fetus (teratogenic effects) and, therefore, should not be used during pregnancy due to the risk of birth defects. The range and severity of associated abnormalities of isotretinoin teratogen syndrome are variable.PreventionDue to the severity of the birth defects  Read More