Neonatal listeriosis is a listeria infection acquired trans placentally or during or after delivery. Diagnosis is made by culture or polymerase chain reaction testing of mother and infant.
Treatment of Neonatal Listeriosis
1. Listeriosis is commonly treated with antibiotics.
2. The most commonly prescribed treatment is intravenous ampicillin.
3. Antibiotic gentamicin in combination with ampicillin is also recommended by most physicians.
4. People who cannot tolerate B-lactam antibiotics (such as ampicillin), will be prescribed trimethoprim-sulfamethoxazole as an alternative.
5. Other antibiotics are sometimes recommended.
6. Antibiotic treatment of pregnant women with documented listeriosis may prevent fetus infection.
7. Other possible drugs include ampicillin or penicillin with rifampin or trimethoprim/sulfamethoxazole, trimethoprim/sulfamethoxazole alone, and meropenem, but they have not been well evaluated.
8. Other treatments are symptomatic and supportive.
Prevention of Neonatal Listeriosis
1. Pregnant women should avoid food products with a higher risk of contamination by L. monocytogenes (eg, unpasteurized dairy products, soft cheeses, raw vegetables, prepared deli meats and salads, refrigerated meat spreads, or smoked seafood).
2. Proper food handling, in particular separating uncooked meats from other items during preparation and washing hands, utensils, and cutting boards after handling uncooked foods, is critical.
3. If infection during pregnancy is recognized, treatment may then be given before delivery or intrapartum to prevent vertical transmission, but the usefulness of such treatment is unproven.
Fever,Lethargy,Irritability,Diarrhea,Poor feeding,Vomiting,Respiratory distress,Skin rash consisting of widely spread, small, pale nodules (granulomatosis infantiseptica)
Febrile gastroenteritis,Invasive disease (sepsis, meningitis, meningoencephalitis),Fetal infections causing spontaneous abortions, stillbirth, premature labor, and neonatal disease