Hereditary Central Nervous System Demyelinating Diseases - 20 Studies Found
| Completed |
: Imaging Study of the White Matter Lesions in Children With Metachromatic Leucodystrophy : Late Infantile Metachromatic Leukodystrophy : 2011-03-09 : Other: High-field MRI (3 Teslas) |
| Completed |
: Efficacy METAZYM for the Treatment Metachromatic Leukodystrophy Treated With Hematopoietic Stem Cell Transplantation : Metachromatic Leukodystrophy : 2011-02-23 : Drug: rhARSA intravenous infusion 100U/kg every other week for 18 months |
| Withdrawn |
: An Observational Study of Pediatric Subjects With Globoid Cell Leukodystrophy (GLD) : Leukodystrophy, Globoid Cell : 2010-03-24 |
| Completed |
: Study of Human Central Nervous System (CNS) Stem Cells Transplantation in Pelizaeus-Merzbacher Disease (PMD) Subjects : Pelizaeus-Merzbacher Disease : 2009-10-28 : Biological: HuCNS-SC cells intracerebral transplantation |
| Completed |
: The Natural History of Infantile Globoid Cell Leukodystrophy : Infantile Globoid Cell Leukodystrophy : 2009-09-23 |
| Active, not recruiting |
: Diffusion Tensor Imaging (DTI) in Infants With Krabbe Disease : Krabbe Disease : 2008-11-07 |
| Completed |
: Effect of Warfarin in the Treatment of Metachromatic Leukodystrophy : Metachromatic Leukodystrophy : 2008-05-21 : Drug: Warfarin Oral administration (QD), variable dosage: patients will undergo blood test for PT/INR at |
| Terminated |
: Open-Label Extension Study of Recombinant Human Arylsulfatase A (HGT-1111) in Late Infantile MLD : Late Infantile Metachromatic Leukodystrophy : 2008-05-19 : Drug: HGT-1111 Patients currently dosed with 100 U/kg or 200 U/kg will continue this treatment. Patients |
| Active, not recruiting |
: The Natural History of Metachromatic Leukodystrophy : Metachromatic Leukodystrophy : 2008-03-11 |
| Completed |
: Long-term Metazym Treatment of Patients With Late Infantile Metachromatic Leukodystrophy (MLD) : Late Infantile Metachromatic Leukodystrophy : 2008-02-29 : Biological: Recombinant human Arylsulfatase A (rhASA) intravenous infusion, every other week for 26 week |